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Did you mean rhoa and blood (2,129 results)?
RHOQ is induced by DLL4 and regulates angiogenesis by determining the intracellular route of the Notch intracellular domain.
Bridges E, Sheldon H, Kleibeuker E, Ramberger E, Zois C, Barnard A, Harjes U, Li JL, Masiero M, MacLaren R, Harris A. Bridges E, et al. Angiogenesis. 2020 Aug;23(3):493-513. doi: 10.1007/s10456-020-09726-w. Epub 2020 Jun 6. Angiogenesis. 2020. PMID: 32506201 Free PMC article.
However, the downstream targets and pathways effected by Delta-like 4 (DLL4)/Notch signalling and their subsequent contribution to angiogenesis are not fully understood. We found that the Rho GTPase, RHOQ, is induced by DLL4 signalling and that silencing RHOQ result …
However, the downstream targets and pathways effected by Delta-like 4 (DLL4)/Notch signalling and their subsequent contribution to angiogene …
Peripheral blood signature of vasodilator-responsive pulmonary arterial hypertension.
Hemnes AR, Trammell AW, Archer SL, Rich S, Yu C, Nian H, Penner N, Funke M, Wheeler L, Robbins IM, Austin ED, Newman JH, West J. Hemnes AR, et al. Circulation. 2015 Jan 27;131(4):401-9; discussion 409. doi: 10.1161/CIRCULATIONAHA.114.013317. Epub 2014 Oct 31. Circulation. 2015. PMID: 25361553 Free PMC article.
We hypothesized that VR-PAH has a different molecular cause from VN-PAH that can be detected in the peripheral blood. METHODS AND RESULTS: Microarrays of cultured lymphocytes from VR-PAH and VN-PAH patients followed at Vanderbilt University were performed with quantitative …
We hypothesized that VR-PAH has a different molecular cause from VN-PAH that can be detected in the peripheral blood. METHODS AND RES …
RhoJ Regulates α5β1 Integrin Trafficking to Control Fibronectin Remodeling during Angiogenesis.
Sundararaman A, Fukushima Y, Norman JC, Uemura A, Mellor H. Sundararaman A, et al. Curr Biol. 2020 Jun 8;30(11):2146-2155.e5. doi: 10.1016/j.cub.2020.03.042. Epub 2020 Apr 16. Curr Biol. 2020. PMID: 32302585 Free article.
Cdc42 underwent gene duplication to produce two related proteins-RhoQ and RhoJ [2]. RhoQ is active in neural dynamics; however, RhoJ is highly expressed in endothelial cells under control of the endothelial-specific promoter ERG [3, 4]. ...These studies identify a c …
Cdc42 underwent gene duplication to produce two related proteins-RhoQ and RhoJ [2]. RhoQ is active in neural dynamics; however …
The Small Rho GTPase TC10 Modulates B Cell Immune Responses.
Burbage M, Keppler SJ, Montaner B, Mattila PK, Batista FD. Burbage M, et al. J Immunol. 2017 Sep 1;199(5):1682-1695. doi: 10.4049/jimmunol.1602167. Epub 2017 Jul 26. J Immunol. 2017. PMID: 28747344 Free PMC article.
In this study, we focus on a close homolog of Cdc42, TC10 (also known as RhoQ), and investigate its physiological role in B cells. By generating a TC10-deficient mouse model, we show that despite reduced total B cell numbers, B cell development in these mice occurs normall …
In this study, we focus on a close homolog of Cdc42, TC10 (also known as RhoQ), and investigate its physiological role in B cells. By …
Alzheimer's disease large-scale gene expression portrait identifies exercise as the top theoretical treatment.
Hill MA, Gammie SC. Hill MA, et al. Sci Rep. 2022 Oct 13;12(1):17189. doi: 10.1038/s41598-022-22179-z. Sci Rep. 2022. PMID: 36229643 Free PMC article.
The three most dysregulated genes in the AD portrait were the inositol trisphosphate kinase, ITPKB (upregulated), the astrocyte specific intermediate filament protein, GFAP (upregulated), and the rho GTPase, RHOQ (upregulated). 41 of the top AD dysregulated genes were also …
The three most dysregulated genes in the AD portrait were the inositol trisphosphate kinase, ITPKB (upregulated), the astrocyte specific int …
Genome-wide association studies identified novel loci for non-high-density lipoprotein cholesterol and its postprandial lipemic response.
An P, Straka RJ, Pollin TI, Feitosa MF, Wojczynski MK, Daw EW, O'Connell JR, Gibson Q, Ryan KA, Hopkins PN, Tsai MY, Lai CQ, Province MA, Ordovas JM, Shuldiner AR, Arnett DK, Borecki IB. An P, et al. Hum Genet. 2014 Jul;133(7):919-30. doi: 10.1007/s00439-014-1435-3. Epub 2014 Mar 7. Hum Genet. 2014. PMID: 24604477 Free PMC article.
The best association signal was found in a tri-genic region at RHOQ-PIGF-CRIPT for baseline NHDL (lead SNP rs6544903, discovery p = 7e-7, MAF = 2 %; validation p = 6e-4 at 0.1 kb upstream neighboring SNP rs3768725, and 5e-4 at 0.7 kb downstream neighboring SNP rs6733143, M …
The best association signal was found in a tri-genic region at RHOQ-PIGF-CRIPT for baseline NHDL (lead SNP rs6544903, discovery p = 7 …
12 results